The present study investigated the cardio-respiratory function, body composition, abdominal muscular strength & endurance and flexibility of Punjab state Kandi and Non-Kandi area boys. In this study, the subjects for data collection were drawn from the different government schools of Kandi and Non-Kandi areas of Punjab state. Random sampling technique was used to select the subjects. The sample consisted of one thousand and fifty (N=1050) boys of Kandi and Non- Kandi area of Punjab state. To measure maximal functional capacity and endurance of the cardio- respiratory system of the subjects, the 9-Minute run test was applied. To evaluate the level of fatness in school age boys, the Skinfold Caliper was used. To assess the abdominal muscular strength & endurance of the subjects, modified sit-ups test was applied. Sit and reach test was used to evaluate the flexibility (extensibility) of the low back and posterior thighs of the subjects. The„t‟ test was applied to find out the significant differences between Kandi and Non-Kandi area boys. To test the hypothesis, the level of significance was set at 0.05. The results showed that Kandi area boys 15-16 years (class 10th) exhibited significantly better maximal functional capacity & endurance, body composition and flexibility (extensibility) of the low back and posterior thighs than Non-Kandi area boys 15-16 years (class 10th). Similarly the Kandi area boys 15-16 years (class 10th) demonstrated better abdominal muscular strength & endurance than Non-Kandi area boys 15-16 years (class 10th) but not significantly.